Associate Professor Deborah Marsh

Associate Professor & Research Only Academic Level D
Medicine, Northern Clinical School
Kolling Institute of Medical Research

E25 - Royal North Shore Hospital
The University of Sydney
NSW 2006 Australia

T:+61 2 9926 4760
F:+61 2 9926 8484
E:

Research interests

The molecular nature of endocrine tumorigenesis

Publications

2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003

2009

  
  • Meyer-Rochow, G., Smith, J., Richardson, A., Marsh, D., Sidhu, S., Robinson, B., Benn, D. Denaturing High Performance Liquid Chromatography Detection of SDHB, SDHD, and VHL Germline Mutations in Pheochromocytoma. The Journal of surgical research. 2009; 157:55-62. [Abstract]
  • Hahn, M., McDonnell, J., Marsh, D. The effect of disease-associated HRPT2 mutations on splicing. Journal of Endocrinology. 2009; 201:387-396. [Abstract]
  • Howell, V., Gill, A., Clarkson, A., Nelson, A., Dunne, R., Delbridge, L., Robinson, B., Teh, B., Gimm, O., Marsh, D. Accuracy of combined protein gene product 9.5 and parafibromin markers for immunohistochemical diagnosis of parathyroid carcinoma. The Journal of clinical endocrinology and metabolism. 2009; 94:434-41. [Abstract]

2008

  
  • Marsh, D., Trahair, T., Martin, J., Chee, W., Walker, J., Kirk, E., Baxter, R., Marshall, G. Rapamycin treatment for a child with germline PTEN mutation. Nature clinical practice. Oncology. 2008; 5:357-61. [Abstract]
  • Marsh, D., Zori, R. Cowden Syndrome. In: Encyclopedia of Cancer, Vol. 1. Germany: Springer 2008. p. 0.

2007

  
  • Hahn, M., Marsh, D. Nucleolar localization of parafibromin is mediated by three nucleolar localization signals. FEBS letters. 2007; 581:5070-4. [Abstract]
  • Marsh, D., Hahn, M., Howell, V., Gill, A. Molecular diagnosis of primary hyperparathyroidism in familial cancer syndromes. Expert Opinion on Medical Diagnostics. 2007; 1:377-392.

2006

  
  • Howell, V., Cardinal, J., Richardson, A., Gimm, O., Robinson, B., Marsh, D. Rapid Mutation Screening for HRPT2 and MEN1 Mutations Associated with Familial and Sporadic Primary Hyperparathyroidism. The Journal of molecular diagnostics : JMD. 2006; 8:559-66. [Abstract]
  • Gill, A., Clarkson, A., Gimm, O., Keil, J., Dralle, H., Howell, V., Marsh, D. Loss of Nuclear Expression of Parafibromin Distinguishes Parathyroid Carcinomas and Hyperparathyroidism-Jaw Tumor (HPT-JT) Syndrome-related Adenomas From Sporadic Parathyroid Adenomas and Hyperplasias. The American journal of surgical pathology. 2006; 30:1140-1149. [Abstract]
  • Benn, D., Richardson, A., Marsh, D., Robinson, B. Genetic testing in pheochromocytoma- and paraganglioma-associated syndromes. Annals of the New York Academy of Sciences. 2006; 1073:104-11. [Abstract]
  • Benn, D., Gimenez-Roqueplo, A., Reilly, J., Bertherat, J., Burgess, J., Byth, K., Croxson, M., Dahia, P., Elston, M., Gimm, O., Henley, D., Herman, P., Murday, V., Niccoli-Sire, P., Pasieka, J., Rohmer, V., Tucker, K., Jeunemaitre, X., Marsh, D., Plouin, P., Robinson, B. Clinical presentation and penetrance of Pheochromocytoma/ Paraganglioma syndromes. The Journal of clinical endocrinology and metabolism. 2006; 91:827-36. [Abstract]
  • Benn, D., Gimenez-Roqueplo, A., Reilly, J., Bertherat, J., Burgess, J., Byth, K., Croxson, M., Dahia, P., Elston, M., Gimm, O., Henley, D., Herman, P., Murday, V., Niccoli-Sire, P., Pasieka, J., Rohmer, V., Tucker, K., Jeunemaitre, X., Marsh, D., Plouin, P., Robinson, B. Clinical presentation and penetrance of pheochromocytoma/paraganglioma syndromes. Journal of Clinical Endocrinology and Metabolism. 2006; 91:827-836. [Abstract]
  • Moscova, M., Marsh, D., Baxter, R. Protein chip discovery of secreted proteins regulated by the phosphatidylinositol 3-kinase pathway in ovarian cancer cell lines. Cancer research. 2006; 66:1376-83. [Abstract]
  • Gimm, O., Lorenz, K., Nguyen Thanh, P., Schneyer, U., Bloching, M., Howell, V., Marsh, D., Teh, B., Krause, U., Dralle, H. [Prophylactic parathyroidectomy for familial parathyroid carcinoma]. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen. 2006; 77:15-24. [Abstract]

2005

  
  • Moscova, M., Marsh, D., Baxter, R. Identification of Cytokines regulated by phosphatidylinositol-3 kinase in ovarian cancer. Clinical Cancer Research. 2005; 11:8977S-8977S. [Abstract]
  • Hahn, M., Marsh, D. Identification of a functional bipartite nuclear localization signal in the tumor suppressor parafibromin. Oncogene. 2005; 24:6241-8. [Abstract]
  • Dahia, P., Ross, K., Wright, M., Hayashida, C., Santagata, S., Barontini, M., Kung, A., Sanso, G., Powers, J., Tischler, A., Hodin, R., Heitritter, S., Moore, F., Dluhy, R., Sosa, J., Ocal, I., Benn, D., Marsh, D., Robinson, B., Schneider, K., Garber, J., Arum, S., Korbonits, M., Grossman, A., Pigny, P., Toledo, S., Nose, V., Li, C., Stiles, C. A HIF1 alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas. Plos Genetics. 2005; 1:72-80. [Abstract]
  • Marsh, D., Benn, D. Von Hippel-Lindau Disease. In: Encyclopedia of Diagnostics Genomics and Proteomics. New York: Marcel Dekker 2005. p. 1329-1333.
  • Marsh, D., Zori, R. Cowden Syndrome. In: Encyclopaedia of Diagnostics Genomics and Proteomics. New York: Marcel Dekker Inc. 2005. p. 301-304.

2004

  
  • Haven, C., Howell, V., Eilers, P., Dunne, R., Takahashi, M., van Puijenbroek, M., Furge, K., Kievit, J., Tan, M., Fleuren, G., Robinson, B., Delbridge, L., Philips, J., Nelson, A., Krause, U., Dralle, H., Hoang-Vu, C., Gimm, O., Morreau, H., Marsh, D., Teh, B. Gene expression of parathyroid tumors: molecular subclassification and identification of the potential malignant phenotype. Cancer research. 2004; 64:7405-11. [Abstract]
  • Howell, V., Zori, R., Stalker, H., Williams, C., Jesse, N., Nelson, A., Robinson, B., Marsh, D. A molecular diagnosis of hyperparathyroidism-jaw tumor syndrome in an adolescent with recurrent kidney stones. The Journal of pediatrics. 2004; 145:567. [Abstract]
  • McDonnell, C., Benn, D., Marsh, D., Robinson, B., Zacharin, M. K40E: a novel succinate dehydrogenase (SDH)B mutation causing familial phaeochromocytoma and paraganglioma. Clinical endocrinology. 2004; 61:510-4. [Abstract]
  • Kirk, E., Smith, J., Field, M., Marshall, G., Marsh, D. Diagnosis of Proteus syndrome was correct. American Journal of Medical Genetics. Part A. 2004. p. 214-5; author reply 216-7. [Abstract]
  • Marsh, D., Morreau, H., Teh, B. HRPT2 and parathyroid cancer. The lancet oncology. 2004. p. 78. [Abstract]
  • Teh, B., Howell, V., Haven, C., Kahnoski, K., Khoo, S., Petillo, D., Chen, J., Fleuren, G., Robinson, B., Delbridge, L., Philips, J., Nelson, A., Krause, U., Hammje, K., Dralle, H., Hoang-Vu, C., Gimm, O., Marsh, D., Morreau, H. Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome. Human genetics. 2004; 114:221-224. [Abstract]

2003

  
  • Zhou, X., Marsh, D., Morrison, C., Chaudhury, A., Maxwell, M., Reifenberger, G., Eng, C. Germline inactivation of PTEN and dysregulation of the phosphoinositol-3-kinase/Akt pathway cause human Lhermitte-Duclos disease in adults. American journal of human genetics. 2003; 73:1191-1198. [Abstract]
  • Howell, V., Haven, C., Kahnoski, K., Khoo, S., Petillo, D., Chen, J., Fleuren, G., Robinson, B., Delbridge, L., Philips, J., Nelson, A., Krause, U., Hammje, K., Dralle, H., Hoang-Vu, C., Gimm, O., Marsh, D., Morreau, H., Teh, B. HRPT2 mutations are associated with malignancy in sporadic parathyroid tumours. Journal of medical genetics. 2003; 40:657-63. [Abstract]
  • Gimm, O., Marsh, D. Does a somatic deletion in RET clarify the sporadic nature of medullary thyroid carcinoma?. Journal of endocrinological investigation. 2003. p. 381-383. [Abstract]
  • Marsh, D., Theodosopoulos, G., Martin-Schulte, K., Richardson, A., Philips, J., Röher, H., Delbridge, L., Robinson, B. Genome-wide copy number imbalances identified in familial and sporadic medullary thyroid carcinoma. The Journal of clinical endocrinology and metabolism. 2003; 88:1866-72. [Abstract]
  • Benn, D., Croxson, M., Tucker, K., Bambach, C., Richardson, A., Delbridge, L., Pullan, P., Hammond, J., Marsh, D., Robinson, B. Novel succinate dehydrogenase subunit B (SDHB) mutations in familial phaeochromocytomas and paragangliomas, but an absence of somatic SDHB mutations in sporadic phaeochromocytomas. Oncogene. 2003; 22:1358-64. [Abstract]
  • Bernard, M., Sidhu, S., Berger, N., Peix, J., Marsh, D., Robinson, B., Gaston, V., Le Bouc, Y., Gicquel, C. A case report in favor of a multistep adrenocortical tumorigenesis. The Journal of clinical endocrinology and metabolism. 2003; 88:998-1001. [Abstract]
  • Marsh, D. Endocrine Tumors - book review. Cancer Forum. 2003; 27(3):1810-181.

Current national competitive grants*

2010

Protein discovery for breast cancer diagnosis
Baxter R, Moore K, Marsh D, Boyle F, McCarthy N
NHMRC Project Grant ($397,125 over 3 years)

New insights into mammalian gene transcription - the role of parafibromin
Marsh D
ARC Discovery Project ($345,000 over 3 years)

2007

Breast Cancer Tissue Bank
Clarke C, Baxter R, Bilous M, Boyages J, Carpenter J, Forbes J, Friedlander M, Harnett P, Kefford R, Marsh D, Morey A, Scott R, Spigelman A, Sutherland R, Balleine R
National Breast Cancer Foundation Project Grants ($1,455,090 over 5 years)

* Grants administered through the University of Sydney